Consecutive weekends of premier motorbike racing is a welcome sight for petrolheads, and we come bearing exciting news. Somebody has finally ended Marc Marquez’s outrageous win streak, and it was none other than his younger brother Alex, last weekend in Catalonia. Despite the loss, the markets still fancy Marc, who heads the MotoGP San Marino pre-event odds ahead of his sibling and his teammate. Learn about prospects for this weekend as riders touch down on the Adriatic for round 16 of the Championship.
After reading our analysis, check out our partner sportsbooks to get valuable promotions and place bets.
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Schedule and How to Watch the San Marino MotoGP
Contestants congregate at the Misano World Circuit Marco Simoncelli on Friday, September 12 for opening day of San Marino GP weekend. Riders will battle the clock on Friday in the practice sessions, before shifting gears for qualifying and the sprint on Saturday. All eyes are on the grand prize which is up for grabs on September 14, starting at 8:00 am EDT. Follow all the qualifying and racing action throughout the event on Fox Sports 1.
Odds Subject to Change
Please note that the odds provided herein reflect the raw probability odds for this analysis and are based on the information available at the time of publishing. Different sportsbooks may adjust these odds based on market conditions, bettor behaviors, and other factors that could influence the betting landscape.
For a deeper understanding of why odds for alternative sports betting change and how it might affect your betting strategy, we encourage you to read our detailed article: Why Do Alternative Sports Betting Odds Change? Make informed decisions and always check the latest odds with your sportsbook before placing bets.
Best Bets and Odds for 2025 MotoGP San Marino
Grand Prix Winner Odds
Ducati star Marc Marquez touches down in Italy with a 182-point buffer at the top of the Riders’ Championship. “The Ant of Cervera” lines up as the defending champion at this circuit and is fresh off his 13th podium of the campaign. Marquez is the winningest rider this season and holds the all-time win record at this venue, with five titles. He ended a seven-race win streak last weekend, after being toppled by his younger brother. Alex Marquez earned his second MotoGP career victory, ending a shaky run that included a DNF, a 10th, and a 14th-place return. Alex has typically struggled on this asphalt, producing a best return of sixth on his last visit.
Ducati has enjoyed its trips to the Adriatic in recent years, prevailing in three of the last seven. Francesco Bagnaia has contributed two victories to the cause in the last four years and finished second last time out. It looks like a long shot, as Pecco hasn’t stood on the rostrum since Germany. Consistency seems to be an issue for Maco Bezzecchi, who has three top-three finishes to his name in the last five starts and two DNFs. The KTM’s have started to find their rhythm late in the season, courtesy of Pedro Acosta, who’s posted four consecutive top fives, including two podiums.
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Player
Event Winner
Payout on $20
Marc Marquez
-250
$28.00
Alex Marquez
+400
$100.00
Francesco Bagnaia
+900
$200.00
Marco Bezzecchi
+1100
$240.00
Enea Bastianini
+1400
$300.00
Fabio Quartararo
+1600
$340.00
Pedro Acosta
+1600
$340.00
Fabio Di Giannantonio
+2900
$600.00
Franco Morbidelli
+3900
$800.00
Brad Binder
+4900
$1,000.00
Johann Zarco
+4900
$1,000.00
Jorge Martin
+5900
$1,200.00
Fermin Aldeguer
+5900
$1,200.00
Pol Espargaro
+9900
$2,000.00
Joan Mir
+9900
$2,000.00
Maverick Vinales
+9900
$2,000.00
Miguel Oliveira
+9900
$2,000.00
Luca Marini
+9900
$2,000.00
Jack Miller
+9900
$2,000.00
Raul Fernandez
+9900
$2,000.00
Ai Ogura
+9900
$2,000.00
Alex Rins
+24900
$5,000.00
Aleix Espargaro
+49900
$10,000.00
Augusto Fernandez
+74900
$15,000.00
Somkiat Chantra
+74900
$15,000.00
Lorenzo Savadori
+74900
$15,000.00
Michele Pirro
+74900
$15,000.00
Expert Pick
We’re sticking with the tried and tested for MotoGP San Marino. Marc Marquez has barely put a foot wrong this season, and while he did lose out to his brother last weekend, he’s entered Victory Lane seven times in the previous eight races. His dominance translates into short odds of -250, which potentially pays $28.00 on a $20 bet.
Where to Bet on MotoGP
Francesco Bagnaia finished second to Marc Marquez here last year. This time around, they’re on the same team. Can Ducati produce the winning bike, and will Pecco exact his revenge against the Riders’ Championship leader? Or does Alex Marquez have other plans for his older rivals? See how the checkered flag drops on Sunday in Italy.
Visit our partner sportsbooks to access special deals that will elevate your betting experience as you anticipate the upcoming Red Bull Grand Prix of San Marino. If you’re a newbie in the world of MotoGP betting, our comprehensive MotoGP Betting Guide is a must-read. Remember to enjoy the race and make your betting choices wisely. Betting responsibly ensures the fun lasts all season long.
KTM arrived at the Sepang test with a revised 2026 RC16 package, featuring a new chassis concept, updated aero parts, and a new swingarm. The team opted to split its factory program between development and consolidation. The strategy paid early dividends after the team completed the opening day as the second-fastest on the timesheets behind Ducati, with Tech3’s Maverick Viñales posting a late 1:57.295 that underlined early pace. KTM used the day to validate the new parts. The team ran a dual approach with Pedro Acosta concentrated on chassis and aerodynamic development, while Brad Binder followed a more conservative program aimed at regaining outright speed.
Acosta, 21, described the new shortened chassis as “promising” and said the configuration was “working,” but he also reported unusual vibrations from the very first lap and limited his opening-day running. He spent his morning exploring chassis setups, used more of his tire allocation than planned, completed an early medium-tire run before switching to softs, and finished 15th on the combined times. He left the day, planning further aero work to improve turning and front-end stability. Acosta’s program prioritized feel and component evaluation over time-attack laps, and KTM noted these early mechanical and stability signals while managing run plans.
Binder, 30, posted consistent lap times around 2:00.2–2:00.3 and initially rode the same chassis he used in Valencia, reporting little chattering as he worked on pace. He also compared the new swingarm against the older design to assess differences, while Acosta focused on aero and chassis feel. Both riders and the factory expected Wednesday to be the main day for further aerodynamic and component evaluations, and KTM said a more definitive assessment of tire behavior and the updated package should become clearer towards the end of the test. The opening session, therefore, underscored KTM’s two-track strategy and highlighted the specific areas, including front-end stability, vibrations, and tire behavior, that the team needs to address before the season.
The “Greatest Show on Dirt” returns to River Cities Speedway for the second time this campaign on Friday night. Michael Kofoid prevailed when the series last rolled into Grand Forks in May. David Gravel finished second on that occasion, but the series leader tops the 2nd Leg of World of Outlaws Northern Tour pre-event odds, …
MotoGP returns to Mugello for the Brembo GP of Italy this weekend. Ducati Lenovo said Marc Marquez has been medically cleared to race but will be reassessed after FP1 to confirm he can continue, following a right-foot fracture and surgery earlier this month and a recent operation to remove a loose screw from his right shoulder. Luca Marini said he is fit and ready after missing the 2025 Mugello with a testing injury and rejected Ducati’s suggestion he become a test rider, saying, “Right now, being a test rider isn’t what I want.” Jorge Martín said he feels ready to tackle Mugello but not fully recovered after several crashes in Barcelona, adding, “At Mugello, you’ve got to show your attributes!”
The championship picture raises the stakes. Marco Bezzecchi leads the standings by 15 points over teammate Jorge Martín after Barcelona, with Aprilia running four bikes inside the top six overall. Fabio Di Giannantonio arrives off his second MotoGP win in Barcelona. Francesco Bagnaia is a three-time Mugello winner (2022–24) and finished third in Barcelona. Pedro Acosta took pole in Barcelona, narrowly missed the Sprint win and was taken out on Sunday, but remains within striking distance of the title.
Injury absences and lineup changes continue to affect the grid. Alex Marquez fractured his C7 vertebra in the Catalan incident and will be replaced in Italy by test rider Michele Pirro. Johann Zarco suffered knee ligament damage in the same crash and will miss Mugello; Cal Crutchlow will step in for Italy. Zarco will also miss the Suzuka 8 Hours and be replaced there by Somkiat Chantra. Marini plans to start the Mugello weekend on a setup similar to his Barcelona configuration, aiming to reach the top ten in pre-qualifying and shift the weekend’s momentum. He prefers dry conditions while acknowledging Honda’s strengths in the wet, and he has a Safety Commission meeting scheduled with other riders, including Bagnaia and Bezzecchi, to discuss rider representation.
A symphony of power will echo through the streets of Birmingham this weekend as the superbikes pull into town. The focus at MotoAmerica Barber is firmly on the superbikes and supersport classes, but the program is stacked with three days of racing. Josh Herrin enters the round as the pre-event odds favorite in the supersport …
Best Bets: 2025 MotoGP San Marino Pre-Event Odds Analysis
Consecutive weekends of premier motorbike racing is a welcome sight for petrolheads, and we come bearing exciting news. Somebody has finally ended Marc Marquez’s outrageous win streak, and it was none other than his younger brother Alex, last weekend in Catalonia. Despite the loss, the markets still fancy Marc, who heads the MotoGP San Marino pre-event odds ahead of his sibling and his teammate. Learn about prospects for this weekend as riders touch down on the Adriatic for round 16 of the Championship.
After reading our analysis, check out our partner sportsbooks to get valuable promotions and place bets.
Schedule and How to Watch the San Marino MotoGP
Contestants congregate at the Misano World Circuit Marco Simoncelli on Friday, September 12 for opening day of San Marino GP weekend. Riders will battle the clock on Friday in the practice sessions, before shifting gears for qualifying and the sprint on Saturday. All eyes are on the grand prize which is up for grabs on September 14, starting at 8:00 am EDT. Follow all the qualifying and racing action throughout the event on Fox Sports 1.
Odds Subject to Change
Please note that the odds provided herein reflect the raw probability odds for this analysis and are based on the information available at the time of publishing. Different sportsbooks may adjust these odds based on market conditions, bettor behaviors, and other factors that could influence the betting landscape.
For a deeper understanding of why odds for alternative sports betting change and how it might affect your betting strategy, we encourage you to read our detailed article: Why Do Alternative Sports Betting Odds Change? Make informed decisions and always check the latest odds with your sportsbook before placing bets.
Best Bets and Odds for 2025 MotoGP San Marino
Grand Prix Winner Odds
Ducati star Marc Marquez touches down in Italy with a 182-point buffer at the top of the Riders’ Championship. “The Ant of Cervera” lines up as the defending champion at this circuit and is fresh off his 13th podium of the campaign. Marquez is the winningest rider this season and holds the all-time win record at this venue, with five titles. He ended a seven-race win streak last weekend, after being toppled by his younger brother. Alex Marquez earned his second MotoGP career victory, ending a shaky run that included a DNF, a 10th, and a 14th-place return. Alex has typically struggled on this asphalt, producing a best return of sixth on his last visit.
Ducati has enjoyed its trips to the Adriatic in recent years, prevailing in three of the last seven. Francesco Bagnaia has contributed two victories to the cause in the last four years and finished second last time out. It looks like a long shot, as Pecco hasn’t stood on the rostrum since Germany. Consistency seems to be an issue for Maco Bezzecchi, who has three top-three finishes to his name in the last five starts and two DNFs. The KTM’s have started to find their rhythm late in the season, courtesy of Pedro Acosta, who’s posted four consecutive top fives, including two podiums.
swipe to see more
Expert Pick
We’re sticking with the tried and tested for MotoGP San Marino. Marc Marquez has barely put a foot wrong this season, and while he did lose out to his brother last weekend, he’s entered Victory Lane seven times in the previous eight races. His dominance translates into short odds of -250, which potentially pays $28.00 on a $20 bet.
Where to Bet on MotoGP
Francesco Bagnaia finished second to Marc Marquez here last year. This time around, they’re on the same team. Can Ducati produce the winning bike, and will Pecco exact his revenge against the Riders’ Championship leader? Or does Alex Marquez have other plans for his older rivals? See how the checkered flag drops on Sunday in Italy.
Visit our partner sportsbooks to access special deals that will elevate your betting experience as you anticipate the upcoming Red Bull Grand Prix of San Marino. If you’re a newbie in the world of MotoGP betting, our comprehensive MotoGP Betting Guide is a must-read. Remember to enjoy the race and make your betting choices wisely. Betting responsibly ensures the fun lasts all season long.
Related Posts
KTM Validates 2026 RC16 Updates, Ends P2 Behind Ducati
KTM arrived at the Sepang test with a revised 2026 RC16 package, featuring a new chassis concept, updated aero parts, and a new swingarm. The team opted to split its factory program between development and consolidation. The strategy paid early dividends after the team completed the opening day as the second-fastest on the timesheets behind Ducati, with Tech3’s Maverick Viñales posting a late 1:57.295 that underlined early pace. KTM used the day to validate the new parts. The team ran a dual approach with Pedro Acosta concentrated on chassis and aerodynamic development, while Brad Binder followed a more conservative program aimed at regaining outright speed.
Acosta, 21, described the new shortened chassis as “promising” and said the configuration was “working,” but he also reported unusual vibrations from the very first lap and limited his opening-day running. He spent his morning exploring chassis setups, used more of his tire allocation than planned, completed an early medium-tire run before switching to softs, and finished 15th on the combined times. He left the day, planning further aero work to improve turning and front-end stability. Acosta’s program prioritized feel and component evaluation over time-attack laps, and KTM noted these early mechanical and stability signals while managing run plans.
Binder, 30, posted consistent lap times around 2:00.2–2:00.3 and initially rode the same chassis he used in Valencia, reporting little chattering as he worked on pace. He also compared the new swingarm against the older design to assess differences, while Acosta focused on aero and chassis feel. Both riders and the factory expected Wednesday to be the main day for further aerodynamic and component evaluations, and KTM said a more definitive assessment of tire behavior and the updated package should become clearer towards the end of the test. The opening session, therefore, underscored KTM’s two-track strategy and highlighted the specific areas, including front-end stability, vibrations, and tire behavior, that the team needs to address before the season.
Best Bets: 2nd Leg of World of Outlaws Northern Tour Pre-Event Odds Analysis
The “Greatest Show on Dirt” returns to River Cities Speedway for the second time this campaign on Friday night. Michael Kofoid prevailed when the series last rolled into Grand Forks in May. David Gravel finished second on that occasion, but the series leader tops the 2nd Leg of World of Outlaws Northern Tour pre-event odds, …
Marquez cleared for Mugello but to be reassessed after FP1
MotoGP returns to Mugello for the Brembo GP of Italy this weekend. Ducati Lenovo said Marc Marquez has been medically cleared to race but will be reassessed after FP1 to confirm he can continue, following a right-foot fracture and surgery earlier this month and a recent operation to remove a loose screw from his right shoulder. Luca Marini said he is fit and ready after missing the 2025 Mugello with a testing injury and rejected Ducati’s suggestion he become a test rider, saying, “Right now, being a test rider isn’t what I want.” Jorge Martín said he feels ready to tackle Mugello but not fully recovered after several crashes in Barcelona, adding, “At Mugello, you’ve got to show your attributes!”
The championship picture raises the stakes. Marco Bezzecchi leads the standings by 15 points over teammate Jorge Martín after Barcelona, with Aprilia running four bikes inside the top six overall. Fabio Di Giannantonio arrives off his second MotoGP win in Barcelona. Francesco Bagnaia is a three-time Mugello winner (2022–24) and finished third in Barcelona. Pedro Acosta took pole in Barcelona, narrowly missed the Sprint win and was taken out on Sunday, but remains within striking distance of the title.
Injury absences and lineup changes continue to affect the grid. Alex Marquez fractured his C7 vertebra in the Catalan incident and will be replaced in Italy by test rider Michele Pirro. Johann Zarco suffered knee ligament damage in the same crash and will miss Mugello; Cal Crutchlow will step in for Italy. Zarco will also miss the Suzuka 8 Hours and be replaced there by Somkiat Chantra. Marini plans to start the Mugello weekend on a setup similar to his Barcelona configuration, aiming to reach the top ten in pre-qualifying and shift the weekend’s momentum. He prefers dry conditions while acknowledging Honda’s strengths in the wet, and he has a Safety Commission meeting scheduled with other riders, including Bagnaia and Bezzecchi, to discuss rider representation.
Best Bets: 2026 MotoAmerica Barber Pre-Event Odds Analysis
A symphony of power will echo through the streets of Birmingham this weekend as the superbikes pull into town. The focus at MotoAmerica Barber is firmly on the superbikes and supersport classes, but the program is stacked with three days of racing. Josh Herrin enters the round as the pre-event odds favorite in the supersport …