In Moto2, Celestino Vietti set the pace at the Catalan Grand Prix, topping both morning and afternoon practice sessions. He led FP1 with a 1:42.028 lap on the Beta Tools SpeedRS Team Boscoscuro and was fastest again in the afternoon with a 1:41.611, both runs on Pirelli control tires. Senna Agius finished second in FP1 with a 1:42.453 on the Liqui Moly Dynavolt Intact GP Kalex and was runner-up in the afternoon with a 1:41.625. Alex Escrig was third in FP1 with a 1:42.567, and Alonso Lopez moved into third in the afternoon with a 1:41.637.

Other Moto2 session highlights included Izan Guevara fourth in FP1 (1:42.608) and fifth in the afternoon (1:41.827), Manuel Gonzalez fifth in FP1 (1:42.706), and Daniel Holgado fourth in the afternoon (1:41.815). The two 27-rider sessions showcased Boscoscuro and Kalex machinery and produced early weekend benchmarks. American Joe Roberts was 20th in the morning (1:43.786) and 21st in the afternoon (1:42.742). Xabi Zurutuza was slowest in FP1, 27th on 1:44.936.

Alex Marquez topped the MotoGP FP1 timesheets at the Circuit de Barcelona-Catalunya with a lap of 1:39.950. Jorge Martín had led for much of the session before finishing 0.349 seconds adrift in second and suffering a heavy crash at Turn 12 after earlier brushing his shoulder at Turn 5 and returning to the Aprilia garage. Pedro Acosta and Marco Bezzecchi completed the FP1 top five, 0.438 seconds and 0.472 seconds off the pace respectively. KTM rider Brad Binder also suffered a crash during FP1.

Reigning champion Marc Marquez was absent from the Catalan weekend after shoulder surgery to remove two damaged screws and a bone fragment that had compressed his radial nerve, and his Le Mans foot fracture was reported as stabilized. Tech3’s Maverick Viñales returned to action after missing three grands prix, and Yamaha test rider Augusto Fernández made a second MotoGP wildcard appearance at the Catalan round.