Consecutive weekends of premier motorbike racing is a welcome sight for petrolheads, and we come bearing exciting news. Somebody has finally ended Marc Marquez’s outrageous win streak, and it was none other than his younger brother Alex, last weekend in Catalonia. Despite the loss, the markets still fancy Marc, who heads the MotoGP San Marino pre-event odds ahead of his sibling and his teammate. Learn about prospects for this weekend as riders touch down on the Adriatic for round 16 of the Championship.
After reading our analysis, check out our partner sportsbooks to get valuable promotions and place bets.
Contestants congregate at the Misano World Circuit Marco Simoncelli on Friday, September 12 for opening day of San Marino GP weekend. Riders will battle the clock on Friday in the practice sessions, before shifting gears for qualifying and the sprint on Saturday. All eyes are on the grand prize which is up for grabs on September 14, starting at 8:00 am EDT. Follow all the qualifying and racing action throughout the event on Fox Sports 1.
Odds Subject to Change
Please note that the odds provided herein reflect the raw probability odds for this analysis and are based on the information available at the time of publishing. Different sportsbooks may adjust these odds based on market conditions, bettor behaviors, and other factors that could influence the betting landscape.
For a deeper understanding of why odds for alternative sports betting change and how it might affect your betting strategy, we encourage you to read our detailed article: Why Do Alternative Sports Betting Odds Change? Make informed decisions and always check the latest odds with your sportsbook before placing bets.
Best Bets and Odds for 2025 MotoGP San Marino
Grand Prix Winner Odds
Ducati star Marc Marquez touches down in Italy with a 182-point buffer at the top of the Riders’ Championship. “The Ant of Cervera” lines up as the defending champion at this circuit and is fresh off his 13th podium of the campaign. Marquez is the winningest rider this season and holds the all-time win record at this venue, with five titles. He ended a seven-race win streak last weekend, after being toppled by his younger brother. Alex Marquez earned his second MotoGP career victory, ending a shaky run that included a DNF, a 10th, and a 14th-place return. Alex has typically struggled on this asphalt, producing a best return of sixth on his last visit.
Ducati has enjoyed its trips to the Adriatic in recent years, prevailing in three of the last seven. Francesco Bagnaia has contributed two victories to the cause in the last four years and finished second last time out. It looks like a long shot, as Pecco hasn’t stood on the rostrum since Germany. Consistency seems to be an issue for Maco Bezzecchi, who has three top-three finishes to his name in the last five starts and two DNFs. The KTM’s have started to find their rhythm late in the season, courtesy of Pedro Acosta, who’s posted four consecutive top fives, including two podiums.
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Player
Event Winner
Payout on $20
Marc Marquez
-250
$28.00
Alex Marquez
+400
$100.00
Francesco Bagnaia
+900
$200.00
Marco Bezzecchi
+1100
$240.00
Enea Bastianini
+1400
$300.00
Fabio Quartararo
+1600
$340.00
Pedro Acosta
+1600
$340.00
Fabio Di Giannantonio
+2900
$600.00
Franco Morbidelli
+3900
$800.00
Brad Binder
+4900
$1,000.00
Johann Zarco
+4900
$1,000.00
Jorge Martin
+5900
$1,200.00
Fermin Aldeguer
+5900
$1,200.00
Pol Espargaro
+9900
$2,000.00
Joan Mir
+9900
$2,000.00
Maverick Vinales
+9900
$2,000.00
Miguel Oliveira
+9900
$2,000.00
Luca Marini
+9900
$2,000.00
Jack Miller
+9900
$2,000.00
Raul Fernandez
+9900
$2,000.00
Ai Ogura
+9900
$2,000.00
Alex Rins
+24900
$5,000.00
Aleix Espargaro
+49900
$10,000.00
Augusto Fernandez
+74900
$15,000.00
Somkiat Chantra
+74900
$15,000.00
Lorenzo Savadori
+74900
$15,000.00
Michele Pirro
+74900
$15,000.00
Expert Pick
We’re sticking with the tried and tested for MotoGP San Marino. Marc Marquez has barely put a foot wrong this season, and while he did lose out to his brother last weekend, he’s entered Victory Lane seven times in the previous eight races. His dominance translates into short odds of -250, which potentially pays $28.00 on a $20 bet.
Where to Bet on MotoGP
Francesco Bagnaia finished second to Marc Marquez here last year. This time around, they’re on the same team. Can Ducati produce the winning bike, and will Pecco exact his revenge against the Riders’ Championship leader? Or does Alex Marquez have other plans for his older rivals? See how the checkered flag drops on Sunday in Italy.
Visit our partner sportsbooks to access special deals that will elevate your betting experience as you anticipate the upcoming Red Bull Grand Prix of San Marino. If you’re a newbie in the world of MotoGP betting, our comprehensive MotoGP Betting Guide is a must-read. Remember to enjoy the race and make your betting choices wisely. Betting responsibly ensures the fun lasts all season long.
Yamaha will become the exclusive motorcycle supplier for the FIM Moto3 World Championship starting in 2028, in a six-year deal through 2033 that will replace the current multi-manufacturer format. The announcement came Thursday at the Dutch Grand Prix in Assen. Moto3 currently uses 250cc four-stroke prototype machines from Honda and KTM, but the class will be standardized around a Yamaha bike under the new plan.
MotoGP chief sporting officer Carlos Ezpeleta said the change is aimed at improving safety, creating more equal competition and lifting racing quality, while also cutting costs to about half of current levels. He said the move should not weaken Moto3’s status as a world championship, pointing to Moto2 as an example that a spec-engine formula can still produce a respected and competitive series. The new Yamaha prototype is expected to weigh 120 kilograms and produce about 90 horsepower, with one report saying it will be built around Yamaha’s R7 engine.
Yamaha said the new Moto3 machine will be a racing prototype based on its CP2 production platform and re-engineered for Grand Prix competition with a better power-to-weight ratio and a full-size chassis for young riders. Prototype testing is scheduled for later in 2026, with a formal unveiling planned for 2027. A lower-spec version is expected to be introduced in the Moto3 Junior World Championship in 2029, and MotoGP and Yamaha are also discussing possible use of the platform in other regional championships as part of the development path for young riders.
Fabio Di Giannantonio’s hard, fair wheel-to-wheel duel with seven-time champion Marc Márquez defined his weekend at the 2026 Brazilian MotoGP, as he emerged third on the podium after a lengthy fight described as “aggressive but clean.” Di Giannantonio said he studied Márquez’s precision — particularly through left-hand turns — and “picked up a lot of ideas” about how to tackle the Spaniard in future races. The result gave Ducati its first podium of the year in the longer main race and was particularly meaningful to Di Giannantonio because it came from direct on-track combat with such an accomplished rival.
The podium followed a difficult build-up: Di Giannantonio had taken pole on Saturday and finished second in the Sprint after two mistakes handed victory to Márquez, then suffered a heavy crash in Sunday morning Warm Up that badly damaged his Ducati Desmosedici. VR46 Ducati mechanics repaired the bike in time and Di Giannantonio started the shortened Grand Prix — which had been cut by eight laps, a decision he learned about roughly six minutes before the race — despite reporting left-shoulder pain and intermittent loss of concentration from impacts under hard braking. He managed the discomfort through the early laps, found a rhythm and climbed to the podium, leaving Brazil with two podiums overall.
The weekend exposed technical gaps as much as it showcased racecraft. Di Giannantonio credited a small setup change and his crew for lifting him among the best Ducatis on the grid, but warned Aprilia had an advantage on the slippery, deteriorating asphalt and said Ducati must work on front-end stability to carry more speed through corners. Márquez, who finished fourth after a front-end washout on a patch of peeling asphalt and early tire discomfort, acknowledged the strength of Aprilia’s package and elected to back off after his off to protect championship points. Di Giannantonio’s podium also shifted the Ducati pecking order: he left Brazil as the top Ducati rider in the standings, three points clear of Márquez and 19 points behind championship leader Marco Bezzecchi. The result underlined both the value of close wheel-to-wheel racing as a development ground and the technical issues teams will need to address going forward; Ducati’s season-long podium run had already been broken in Thailand, ending an uninterrupted streak that dated back to Silverstone 2021.
MotoGP Racing Championship MotoGP is the summit for Hyperactive Motorsport or motorcycle racing. It represents the globe’s top motorcycle riders competing against each other using technologically and powerful advanced motorcycles. It is a global championship involving the best talents worldwide to show off their motorcycle racing skills in different race circuits. The MotoGP motorcycle racing competition …
MotoGP returns to Mugello for the Brembo GP of Italy this weekend. Ducati Lenovo said Marc Marquez has been medically cleared to race but will be reassessed after FP1 to confirm he can continue, following a right-foot fracture and surgery earlier this month and a recent operation to remove a loose screw from his right shoulder. Luca Marini said he is fit and ready after missing the 2025 Mugello with a testing injury and rejected Ducati’s suggestion he become a test rider, saying, “Right now, being a test rider isn’t what I want.” Jorge Martín said he feels ready to tackle Mugello but not fully recovered after several crashes in Barcelona, adding, “At Mugello, you’ve got to show your attributes!”
The championship picture raises the stakes. Marco Bezzecchi leads the standings by 15 points over teammate Jorge Martín after Barcelona, with Aprilia running four bikes inside the top six overall. Fabio Di Giannantonio arrives off his second MotoGP win in Barcelona. Francesco Bagnaia is a three-time Mugello winner (2022–24) and finished third in Barcelona. Pedro Acosta took pole in Barcelona, narrowly missed the Sprint win and was taken out on Sunday, but remains within striking distance of the title.
Injury absences and lineup changes continue to affect the grid. Alex Marquez fractured his C7 vertebra in the Catalan incident and will be replaced in Italy by test rider Michele Pirro. Johann Zarco suffered knee ligament damage in the same crash and will miss Mugello; Cal Crutchlow will step in for Italy. Zarco will also miss the Suzuka 8 Hours and be replaced there by Somkiat Chantra. Marini plans to start the Mugello weekend on a setup similar to his Barcelona configuration, aiming to reach the top ten in pre-qualifying and shift the weekend’s momentum. He prefers dry conditions while acknowledging Honda’s strengths in the wet, and he has a Safety Commission meeting scheduled with other riders, including Bagnaia and Bezzecchi, to discuss rider representation.
Best Bets: 2025 MotoGP San Marino Pre-Event Odds Analysis
Consecutive weekends of premier motorbike racing is a welcome sight for petrolheads, and we come bearing exciting news. Somebody has finally ended Marc Marquez’s outrageous win streak, and it was none other than his younger brother Alex, last weekend in Catalonia. Despite the loss, the markets still fancy Marc, who heads the MotoGP San Marino pre-event odds ahead of his sibling and his teammate. Learn about prospects for this weekend as riders touch down on the Adriatic for round 16 of the Championship.
After reading our analysis, check out our partner sportsbooks to get valuable promotions and place bets.
Schedule and How to Watch the San Marino MotoGP
Contestants congregate at the Misano World Circuit Marco Simoncelli on Friday, September 12 for opening day of San Marino GP weekend. Riders will battle the clock on Friday in the practice sessions, before shifting gears for qualifying and the sprint on Saturday. All eyes are on the grand prize which is up for grabs on September 14, starting at 8:00 am EDT. Follow all the qualifying and racing action throughout the event on Fox Sports 1.
Odds Subject to Change
Please note that the odds provided herein reflect the raw probability odds for this analysis and are based on the information available at the time of publishing. Different sportsbooks may adjust these odds based on market conditions, bettor behaviors, and other factors that could influence the betting landscape.
For a deeper understanding of why odds for alternative sports betting change and how it might affect your betting strategy, we encourage you to read our detailed article: Why Do Alternative Sports Betting Odds Change? Make informed decisions and always check the latest odds with your sportsbook before placing bets.
Best Bets and Odds for 2025 MotoGP San Marino
Grand Prix Winner Odds
Ducati star Marc Marquez touches down in Italy with a 182-point buffer at the top of the Riders’ Championship. “The Ant of Cervera” lines up as the defending champion at this circuit and is fresh off his 13th podium of the campaign. Marquez is the winningest rider this season and holds the all-time win record at this venue, with five titles. He ended a seven-race win streak last weekend, after being toppled by his younger brother. Alex Marquez earned his second MotoGP career victory, ending a shaky run that included a DNF, a 10th, and a 14th-place return. Alex has typically struggled on this asphalt, producing a best return of sixth on his last visit.
Ducati has enjoyed its trips to the Adriatic in recent years, prevailing in three of the last seven. Francesco Bagnaia has contributed two victories to the cause in the last four years and finished second last time out. It looks like a long shot, as Pecco hasn’t stood on the rostrum since Germany. Consistency seems to be an issue for Maco Bezzecchi, who has three top-three finishes to his name in the last five starts and two DNFs. The KTM’s have started to find their rhythm late in the season, courtesy of Pedro Acosta, who’s posted four consecutive top fives, including two podiums.
swipe to see more
Expert Pick
We’re sticking with the tried and tested for MotoGP San Marino. Marc Marquez has barely put a foot wrong this season, and while he did lose out to his brother last weekend, he’s entered Victory Lane seven times in the previous eight races. His dominance translates into short odds of -250, which potentially pays $28.00 on a $20 bet.
Where to Bet on MotoGP
Francesco Bagnaia finished second to Marc Marquez here last year. This time around, they’re on the same team. Can Ducati produce the winning bike, and will Pecco exact his revenge against the Riders’ Championship leader? Or does Alex Marquez have other plans for his older rivals? See how the checkered flag drops on Sunday in Italy.
Visit our partner sportsbooks to access special deals that will elevate your betting experience as you anticipate the upcoming Red Bull Grand Prix of San Marino. If you’re a newbie in the world of MotoGP betting, our comprehensive MotoGP Betting Guide is a must-read. Remember to enjoy the race and make your betting choices wisely. Betting responsibly ensures the fun lasts all season long.
Related Posts
Yamaha to become exclusive Moto3 supplier in 2028 deal
Yamaha will become the exclusive motorcycle supplier for the FIM Moto3 World Championship starting in 2028, in a six-year deal through 2033 that will replace the current multi-manufacturer format. The announcement came Thursday at the Dutch Grand Prix in Assen. Moto3 currently uses 250cc four-stroke prototype machines from Honda and KTM, but the class will be standardized around a Yamaha bike under the new plan.
MotoGP chief sporting officer Carlos Ezpeleta said the change is aimed at improving safety, creating more equal competition and lifting racing quality, while also cutting costs to about half of current levels. He said the move should not weaken Moto3’s status as a world championship, pointing to Moto2 as an example that a spec-engine formula can still produce a respected and competitive series. The new Yamaha prototype is expected to weigh 120 kilograms and produce about 90 horsepower, with one report saying it will be built around Yamaha’s R7 engine.
Yamaha said the new Moto3 machine will be a racing prototype based on its CP2 production platform and re-engineered for Grand Prix competition with a better power-to-weight ratio and a full-size chassis for young riders. Prototype testing is scheduled for later in 2026, with a formal unveiling planned for 2027. A lower-spec version is expected to be introduced in the Moto3 Junior World Championship in 2029, and MotoGP and Yamaha are also discussing possible use of the platform in other regional championships as part of the development path for young riders.
Di Giannantonio third after wheel-to-wheel with Marquez
Fabio Di Giannantonio’s hard, fair wheel-to-wheel duel with seven-time champion Marc Márquez defined his weekend at the 2026 Brazilian MotoGP, as he emerged third on the podium after a lengthy fight described as “aggressive but clean.” Di Giannantonio said he studied Márquez’s precision — particularly through left-hand turns — and “picked up a lot of ideas” about how to tackle the Spaniard in future races. The result gave Ducati its first podium of the year in the longer main race and was particularly meaningful to Di Giannantonio because it came from direct on-track combat with such an accomplished rival.
The podium followed a difficult build-up: Di Giannantonio had taken pole on Saturday and finished second in the Sprint after two mistakes handed victory to Márquez, then suffered a heavy crash in Sunday morning Warm Up that badly damaged his Ducati Desmosedici. VR46 Ducati mechanics repaired the bike in time and Di Giannantonio started the shortened Grand Prix — which had been cut by eight laps, a decision he learned about roughly six minutes before the race — despite reporting left-shoulder pain and intermittent loss of concentration from impacts under hard braking. He managed the discomfort through the early laps, found a rhythm and climbed to the podium, leaving Brazil with two podiums overall.
The weekend exposed technical gaps as much as it showcased racecraft. Di Giannantonio credited a small setup change and his crew for lifting him among the best Ducatis on the grid, but warned Aprilia had an advantage on the slippery, deteriorating asphalt and said Ducati must work on front-end stability to carry more speed through corners. Márquez, who finished fourth after a front-end washout on a patch of peeling asphalt and early tire discomfort, acknowledged the strength of Aprilia’s package and elected to back off after his off to protect championship points. Di Giannantonio’s podium also shifted the Ducati pecking order: he left Brazil as the top Ducati rider in the standings, three points clear of Márquez and 19 points behind championship leader Marco Bezzecchi. The result underlined both the value of close wheel-to-wheel racing as a development ground and the technical issues teams will need to address going forward; Ducati’s season-long podium run had already been broken in Thailand, ending an uninterrupted streak that dated back to Silverstone 2021.
MotoGP Betting Strategies for Beginners and Pros
MotoGP Racing Championship MotoGP is the summit for Hyperactive Motorsport or motorcycle racing. It represents the globe’s top motorcycle riders competing against each other using technologically and powerful advanced motorcycles. It is a global championship involving the best talents worldwide to show off their motorcycle racing skills in different race circuits. The MotoGP motorcycle racing competition …
Marquez cleared for Mugello but to be reassessed after FP1
MotoGP returns to Mugello for the Brembo GP of Italy this weekend. Ducati Lenovo said Marc Marquez has been medically cleared to race but will be reassessed after FP1 to confirm he can continue, following a right-foot fracture and surgery earlier this month and a recent operation to remove a loose screw from his right shoulder. Luca Marini said he is fit and ready after missing the 2025 Mugello with a testing injury and rejected Ducati’s suggestion he become a test rider, saying, “Right now, being a test rider isn’t what I want.” Jorge Martín said he feels ready to tackle Mugello but not fully recovered after several crashes in Barcelona, adding, “At Mugello, you’ve got to show your attributes!”
The championship picture raises the stakes. Marco Bezzecchi leads the standings by 15 points over teammate Jorge Martín after Barcelona, with Aprilia running four bikes inside the top six overall. Fabio Di Giannantonio arrives off his second MotoGP win in Barcelona. Francesco Bagnaia is a three-time Mugello winner (2022–24) and finished third in Barcelona. Pedro Acosta took pole in Barcelona, narrowly missed the Sprint win and was taken out on Sunday, but remains within striking distance of the title.
Injury absences and lineup changes continue to affect the grid. Alex Marquez fractured his C7 vertebra in the Catalan incident and will be replaced in Italy by test rider Michele Pirro. Johann Zarco suffered knee ligament damage in the same crash and will miss Mugello; Cal Crutchlow will step in for Italy. Zarco will also miss the Suzuka 8 Hours and be replaced there by Somkiat Chantra. Marini plans to start the Mugello weekend on a setup similar to his Barcelona configuration, aiming to reach the top ten in pre-qualifying and shift the weekend’s momentum. He prefers dry conditions while acknowledging Honda’s strengths in the wet, and he has a Safety Commission meeting scheduled with other riders, including Bagnaia and Bezzecchi, to discuss rider representation.